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Contributions

2024 |2023 |2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014

2024

  1. Aida S, Ishikawa Y, Kaneko M: Two cases of bronchiolar adenoma with their diagnostic difficulties and important clues. Pathol Int 74: 416-418, 2024.
  2. Kovács Z, Sugimura H, György TA, Osvath E, Manirakiza F, Gurzu S: Bioinformatic Identification of TP53 Gene Mutation Hotspots in Colorectal Cancer. Int J Mol Sci 25: 6612, 2024.
  3. Nzitakera A, Surwumwe JB, Ndoricyimpaye EL, Uwamungu S, Uwamariya D, Manirakiza F, Ndayisaba MC, Ntakirutimana G, Seminega B, Dusabejambo V, Rutaganda E, Kamali P, Ngabonziza F, Ishikawa R, Rugwizangoga B, Iwashita Y, Yamada H, Yoshimura K, Sugimura H, Shinmura K: The spectrum of TP53 mutations in Rwandan patients with gastric cancer. Genes Environ 46: 8, 2024.
  4. Takahashi K, Yachida N, Tamura R, Adachi S, Kondo S, Abé T, Umezu H, Nyuzuki H, Okuda S, Nakaoka H, Yoshihara K: Clonal origin and genomic diversity in Lynch syndrome-associated endometrial cancer with multiple synchronous tumors: Identification of the pathogenicity of MLH1 p.L582H. Genes Chromosomes Cancer 63: e23231, 2024.
  5. Nishimura L, Tanino A, Ajimoto M, Katsumura T, Ogawa M, Koganebuchi K, Waku D, Kumagai M, Sugimoto R, Nakaoka H, Oota H, Inoue I: Metagenomic analyses of 7000 to 5500 years old coprolites excavated from the Torihama shell-mound site in the Japanese archipelago. PLoS One 19: e0295924, 2024.
  6. Yamaguchi H, Miyazaki M: Heterocellular Adhesion in Cancer Invasion and Metastasis: Interactions between Cancer Cells and Cancer-Associated Fibroblasts. Cancers 16: 1636553, 2024.
  7. Akashi H, Yachida N, Ueda H, Yamaguchi M, Yamawaki K, Tamura R, Suda K, Ishiguro T, Adachi S, Nagase Y, Ueda Y, Ueda M, Abiko K, Kagabu M, Baba T, Nakaoka H, Enomoto T, Murai J, Yoshihara K: SLFN11 is a BRCA Independent Biomarker for the Response to Platinum-Based Chemotherapy in High-Grade Serous Ovarian Cancer and Clear Cell Ovarian Carcinoma. Mol Cancer Ther 23: 106-116, 2024.

2023

  1. Mitsunaga S, Fujito N, Nakaoka H, Imazeki R, Nagata E, Inoue I: Detection of APP gene recombinant in human blood plasma. Sci Rep 13: 21703, 2023.
  2. Zhang W#, Miura A#, Abu Saleh MM, Shimizu K, Mita Y, Tanida R, Hirako S, Shioda S, Gmyr V, Kerr-Conte J, Pattou F, Jin C, Kanai Y, Sasaki K, Minamino N, Sakoda H, Nakazato M: The NERP-4-SNAT2 axis regulates pancreatic β-cell maintenance and function. Nature Commun 14: 8158, 2023. #Contributed equally.
  3. Tamura R, Nakaoka H, Yachida N, Ueda H, Ishiguro T, Motoyama T, Inoue I, Enomoto T, Yoshihara K: Spatial genomic diversity associated with APOBEC mutagenesis in squamous cell carcinoma arising from ovarian teratoma. Cancer Science 114: 2145-2157, 2023.
  4. Toyoda Y, Nakatochi M, Nakayama A, Kawamura Y, Nakaoka H, Wakai K, Matsuo K, Matsuo H; Japan Gout Genomics Consortium: SNP-based heritability estimates of gout and its subtypes determined by genome-wide association studies of clinically defined gout. Rheumatology (Oxford) 62: e144-e146, 2023.
  5. Izuo N, Miyanishi H, Nishizawa D, Fujii T, Hasegawa J, Sato N, Tanioka F, Sugimura H, Ikeda K, Nitta A: DNA methylation status of SHATI/NAT8L promoter in the blood of cigarette smokers. Neuropsychopharmacol Rep. Published online.
  6. Kaneko M, Nakashima M, Sugiura K, Ishida N, Tamura S, Tani S, Yamade M, Hamaya Y, Osawa S, Tatsuta K, Kurachi K, Baba S, Iwashita Y, Arai T, Sugimura H, Maekawa M, Sugimoto K, Iwaizumi M: Both MLH1 deficiency and BRAFV600E mutation are a unique characteristic of colorectal medullary carcinoma: An observational study. Medicine (Baltimore) 102: e35022, 2023.
  7. Yamashita T#, Takanashi Y#, Uebayashi A, Oka M, Mizuno K, Kawase A, Oyama S, Kitamoto T, Kondo M, Omori S, Tao H, Takahashi Y, Sakamoto T, Kahyo T, Sugimura H, Setou M, Shiiya N, Funai K: Lung adenocarcinoma and squamous cell carcinoma difficult for immunohistochemical diagnosis can be distinguished by lipid profile. Sci. Rep. 13:12092, 2023. #Contributed equally
  8. Manirakiza F, Rutaganda E, Yamada H, Iwashita Y, Rugwizangoga B, Seminega B, Dusabejambo V, Ntakirutimana G, Ruhangaza D, Uwineza A, Shinmura K, Sugimura H: Clinicopathological Characteristics and Mutational Landscape of APC, HOXB13, and KRAS among Rwandan Patients with Colorectal Cancer. Curr Issues Mol Biol. 45: 4359-4374, 2023.
  9. Manirakiza F, Yamada H, Iwashita Y, Ishino K, Ishikawa R, Kovacs Z, Osvath E, Nzitakera A, Gurzu S, Sugimura H: TP53 mutations in Romanian patients with colorectal cancer. Genes Environ. 45: 20, 2023.
  10. Noguchi R, Kosako H, Sasaki K, Kondo T: Data for proteogenomic analysis of two patient-derived undifferentiated pleomorphic sarcoma cell lines. Journal of Proteome Data and Methods 5: 13, 2023.
  11. Kawabata Kamo Y, Igarashi H, Sugimura H: Modification of Grocott’s staining procedure with heat treatment and oxidation by periodic acid for mucormycosis in tissue: a method to detect Mucor spp. BioTechniques 74: 143-147, 2023.
  12. Katsuragi S, Otsuki Y, Unno S, Kimata M, Yoshizawa Y, Tomatsu M, Shinmura K, Suzuki K, Sugimura H: Evaluation of the widths of the mucosal strips in pathological examination of specimens of endoscopic submucosal dissection for early gastric cancer. Gastric Cancer 26: 755-762, 2023.
  13. Nakamura M, Shiga A, Iimori A, Matsuzaki T: Efficient endocytosis of the human lactoferrin N-lobe enhances its antiproliferative activity against human cancer cells. Biol Pharm Bull. 46: 1004-1009, 2023.
  14. Miyazaki M, Nakabo A, Nagano Y, Nagamura Y, Yanagihara K, Ohki R, Nakamura Y, Fukami K, Kawamoto J, Umayahara K, Sakamoto M, Iwaya K, Yamaguchi H: Tissue factor-induced fibrinogenesis mediates cancer cell clustering and multiclonal peritoneal metastasis. Cancer Letters 553: 215983, 2023.

2022

  1. Banerjee P, Kubo F, Nakaoka H, Ajima R, Sato T, Hirata T, Iwasato T: Spontaneous activity in whisker-innervating region of neonatal mouse trigeminal ganglion. Sci. Rep. 12: 16311, 2022.
  2. Yoshioka A, Nakaoka H, Fukumoto T, Inoue I, Nishigori C, Kunisada M. The landscape of genetic alterations of UVB-induced skin tumors in DNA repair-deficient mice. Exp. Dermatol. 31: 1607-1617, 2022.
  3. Rose MM, Dhamodharan S, Revathidevi S, Chakkarappan SR, Mani JG, Shanmugam S, Nakaoka H, Inoue I, Murugan AK, Munirajan AK: High incidence of PI3K pathway gene mutations in South Indian cervical cancers. Cancer Genet. 264-265: 100-108, 2022.
  4. Yamaguchi H, Nagamura Y, Miyazaki M: Receptor tyrosine kinases amplified in diffuse-type gastric carcinoma: potential targeted therapies and novel downstream effectors. Cancers 14: 3750, 2022.
  5. Paudel D, Kuramitsu Y, Uehara O, Morikawa T, Yoshida K, Giri S, Islam S, Kitagawa T, Kondo T, Sasaki K, Matsuoka H, Miura H, Abiko Y: Proteomic and microbiota analyses of the oral cavity during psychological stress. PLoS ONE 17: e0268155, 2022.
  6. Shirakihara T, Yamaguchi H, Kondo T, Yashiro M, Sakai R: Transferrin receptor 1 promotes the fibroblast growth factor receptor-mediated oncogenic potential of diffused-type gastric cancer. Oncogene 41: 2587-2596, 2022.
  7. Toyoda Y, Nakayama A, Nakatochi M, Kawamura Y, Nakaoka H, Yamamoto K, Shimizu S, Ooyama H, Ooyama K, Shimizu T, Nagase M, Hidaka Y, Ichida K, Inoue I, Shinomiya N, Matsuo H: Japan Gout Genomics Consortium (Japan Gout). Genome-wide meta-analysis between renal overload type and renal underexcretion type of clinically defined gout in Japanese populations. Mol Genet Metab. 136: 186-189, 2022.
  8. Revathidevi S, Nakaoka H, Suda K, Fujito N, Munirajan AK, Yoshihara K, Enomoto T, Inoue I: APOBEC mediated mutagenesis drives genomic heterogeneity in endometriosis.  J Hum Genet. 67: 323-329, 2022.
  9. Iwaya K, Arai H, Takatou N, Morita Y, Ozeki R, Nakaoka H, Sakamoto M, Kouno T, Soma M: A sheet pocket to prevent cross-contamination of formalin-fixed paraffin-embedded block for application in next generation sequencing. PLoS ONE 17: e0266947, 2022.
  10. Sakaue S, Hosomichi K, Hirata J, Nakaoka H, Yamazaki K, Yawata M, Yawata N, Naito T, Umeno J, Kawaguchi T, Matsui T, Motoya S, Suzuki Y, Inoko H, Tajima A, Morisaki T, Matsuda K, Kamatani Y, Yamamoto K, Inoue I, Okada Y: Decoding the diversity of killer immunoglobulin-like receptors by deep sequencing and a high-resolution imputation method. Cell Genomics 2: 100101, 2022.
  11. Takahashi M, Hosomichi K, Nakaoka H, Sakata H, Uesato N, Murakami K, Kano M, Toyozumi T, Matsumoto Y, Isozaki T, Sekino N, Otsuka R, Inoue I, Matsubara H: Biased expression of mutant alleles in cancer-related genes in esophageal squamous cell carcinoma.  Esophagus 19: 294-302, 2022.
  12. Yamaguchi M, Nakaoka H, Suda K, Yoshihara K, Ishiguro T, Yachida N, Saito K, Ueda H, Sugino K, Mori Y, Yamawaki K, Tamura R, Revathidevi S, Motoyama T, Tainaka K, Verhaak RGW, Inoue I, Enomoto T: Spatiotemporal dynamics of clonal selection and diversification in normal endometrial epithelium. Nat Commun. 13: 943, 2022.
  13. Jinam TA, Hosomichi K, Nakaoka H, Phipps ME, Saitou N, Inoue I: Allelic and haplotypic HLA diversity in indigenous Malaysian populations explored using Next Generation Sequencing. Hum Immunol. 83: 17-26, 2022.
  14. Nakamura M and Sato A: Glycan-binding properties of basic whey protein lactoferrin and its application in nerve regenerative medicine.  Trends in Glycoscience and Glycotechnology. 34: E19-E23, 2022.
  15. Miyamoto S, Nagano Y, Miyazaki M, Nagamura Y, Sasaki K, Kawamura T, Yanagihara K, Imai T, Ohki R, Yashiro M, Tanaka M, Sakai R, and Yamaguchi H: Integrin α5 mediates cancer cell-fibroblast adhesion and peritoneal dissemination of diffuse-type gastric carcinoma. Cancer Letters 526: 335-345, 2022.

2021

  1. Toyoda Y, Kawamura Y, Nakayama A, Nakaoka H, Higashino T, Shimizu S, Ooyama H, Morimoto K, Uchida N, Shigesawa R, Takeuchi K, Inoue I, Ichida K, Suzuki H, Shinomiya N, Takada T, Matsuo H: Substantial anti-gout effect conferred by common and rare dysfunctional variants of URAT1/SLC22A12. Rheumatology 60: 5224-5232, 2021.
  2. Tamura R, Yoshihara K, Matsuo K, Yachida N, Miyoshi A, Takahashi K, Sugino K, Yamaguchi M, Mori Y, Suda K, Ishiguro T, Okuda S, Motoyama T, Nakaoka H, Kikuchi A, Ueda Y, Inoue I, and Enomoto T: Proposing a molecular classification associated with hypercoagulation in ovarian clear cell carcinoma. Gynecol. Oncol. 163: 327-333, 2021.
  3. Sugimoto R, Nishimura L, Nguyen PT, Ito J, Parrish NF, Mori H, Kurokawa K, Nakaoka H, Inoue I: Comprehensive discovery of CRISPR-targeted terminally redundant sequences in the human gut metagenome: Viruses, plasmids, and more. PLoS Comput. Biol. 17: e1009428, 2021.
  4. Nagamura Y, Miyazaki M, Nagano Y, Tomiyama A, Ohki R, Yanagihara K, Sakai R, and Yamaguchi H: SHP2 as a potential therapeutic target in diffuse-type gastric carcinoma addicted to receptor tyrosine kinase signaling. Cancers 13: 4309, 2021.
  5. Aamer W, Hassan HY, Nakaoka H, Hosomichi K, Jaeger M, Tahir H, Abdelraheem MH, Netea MG, and Inoue I: Analysis of HLA gene polymorphisms in East Africans reveals evidence of gene flow in two Semitic populations from Sudan. Eur. J. Hum. Genet. 29: 1259-1271, 2021.
  6. Yachida N, Yoshihara K, Suda K, Nakaoka H, Ueda H, Sugino K, Yamaguchi M, Mori Y, Yamawaki K, Tamura R, Ishiguro T, Kase H, Motoyama T, and Enomoto T: Biological significance of KRAS mutant allele expression in ovarian endometriosis. Cancer Sci. 112(5): 2020-2032, 2021.
  7. Yamaguchi M, Yoshihara K, Suda K, Nakaoka H, Yachida N, Ueda H, Sugino K, Mori Y, Yamawaki K, Tamura R, Ishiguro T, Motoyama T, Watanabe Y, Okuda S, Tainaka K, and Enomoto T: Three-dimensional understanding of the morphological complexity of the human uterine endometrium. iScience. 24(4): 102258, 2021.
  8. Matsumoto Y, Nagayama H, Nakaoka H, Toyoda A, Goto T, and Koide T: Combined change of behavioral traits for domestication and gene-networks in mice selectively bred for active tameness. Genes Brain Behav. 20(3): e12721, 2021.
  9. Nishimura L, Sugimoto R, Inoue J, Nakaoka H, Kanzawa-Kiriyama H, Shinoda KI, and Inoue I: Identification of ancient viruses from metagenomic data of the Jomon people. J. Hum. Genet. 66(3): 287-296, 2021.
  10. Nakakura S, Hosomichi K, Uchino S, Murakami A, Oka A, Inoue I, and Nakaoka H: HLA-B*39:01:01 is a novel risk factor for antithyroid drug-induced agranulocytosis in Japanese population. Pharmacogenomics J. 21(1): 94-101, 2021.
  11. Revathidevi S, Murugan AK, Nakaoka H, Inoue I, and Munirajan AK: APOBEC: A molecular driver in cervical cancer pathogenesis. Cancer Lett. 496: 104-116, 2021.
  12. Nagamura Y, Miyazaki M, Nagano Y, Yuki M, Fukami K, Yanagihara K, Sasaki K, Sakai R, and Yamaguchi H: PLEKHA5 regulates the survival and peritoneal dissemination of diffuse-type gastric carcinoma cells with Met gene amplification. Oncogenesis 10: 25, 2021.
  13. Miyazaki S, Tashiro A, Tsuchiya T, Sasaki K, Miyazaki J. Establishment of a long-term stable β-cell line and its application to analyze the effect of Gcg expression on insulin secretion. Scientific Reports 11: 477, 2021.
  14. Nakamura, M., Matsuzaki, T., Iimori, A., and Sato, A. Harnessing the chondroitin sulfate-binding characteristics of human lactoferrin to neutralize neurite outgrowth inhibition. Biochem. Biophys. Res. Comm. 534: 1076-1082, 2021.
  15. Nakano Y, Takadera M, Miyazaki M, Qiao Z, Nakajima K, Noguchi R, Oyama R, Kimura Y, Okuhiro Y, Yamasaki K, Kunihiro N, Fukushima H, Inoue T, Hara J, Ozawa T, Kondo T, and Ichimura K: Drug screening with a novel tumor-derived cell line identified alternative therapeutic options for patients with atypical teratoid/rhabdoid tumor. Human Cell 34: 271-278. 2021.

2020年

  1. Kobayashi T, Miyazaki M, Sasaki N, Yamamuro S, Uchida E, Kawauchi D, Takahashi M, Otsuka Y, Kumagai K, Takeuchi S, Toyooka T, Otani N, Wada K, Narita Y, Yamaguchi H, Muragaki Y, Kawamata T, Mori K, Ichimura K and Tomiyama A: Enhanced malignant phenotypes of glioblastoma cells surviving NPe6-mediated photodynamic therapy are regulated via ERK1/2 activation. Cancers 12: 3641, 2020.
  2. Yoneda A, Kanemaru K, Matsubara A, Takai E, Shimozawa M, Yanagihara K, Satow R, Yamaguchi H, Nakamura Y, and Fukami K: Phosphatidylinositol 4,5-bisphosphate is localized in the outer leaflet of the plasma membrane and regulates cell adhesion and motility. Biochem. Biophys. Res. Comm. 527: 1050-1056, 2020.
  3. Tsuchiya, T., Nakayama, A., Kawamura, T., and Sasaki, K. Capillary electrophoresis electrospray ionization-mass spectrometry for peptidomics-based processing site determination. Biochem. Biophys. Res. Comm. 533: 872-878, 2020.
  4. Ueda, K., Shimizu, M., Ohashi, A., Murata, D., Suzuki, T., Kobayashi, N., Baba, J., Takeuchi, T., Shiga, Y., Nakamura, M., Kagaya, S. and Sato, A. Albumin fusion at the N-terminus or C-terminus of human lactoferrin leads to improved pharmacokinetics and anti-proliferative effects on cancer cell lines. European Journal of Pharmaceutical Sciences 155: 105551, 2020
  5. Yesbolatova A, Saito Y, Kitamoto N, Makino-Itou H, Ajima R, Nakano R, Nakaoka H, Fukui K, Gamo K, Tominari Y, Takeuchi H, Saga Y, Hayashi K, Kanemaki MT. The auxin-inducible degron 2 technology gives superior degradation control in yeast, mammalian cells, and mice. Nature Communications 11: 5701, 2020
  6. Ito J, Kimura I, Soper A, Coudray A, Koyanagi Y, Nakaoka H, Inoue I, Turelli P, Trono D, Sato K. Endogenous retroviruses drive KRAB zinc-finger protein family expression for tumor suppression. Science Advances 6: eabc3020, 2020
  7. Yachida N, Yoshihara K, Suda K, Nakaoka H, Ueda H, Sugino K, Yamaguchi M, Mori Y, Yamawaki K, Tamura R, Ishiguro T, Isobe M, Motoyama T, Inoue I, Enomoto T. ARID1A protein expression is retained in ovarian endometriosis with ARID1A loss-of-function mutations: Implication for the two-hit hypothesis. Scientific Reports 10: 14260, 2020
  8. Kantake M, Ikeda N, Nakaoka H, Ohkawa N, Tanaka T, Miyabayashi K, Shoji H, Shimizu T. IGF1 gene is epigenetically activated in preterm infants with intrauterine growth restriction. Clin Epigenetics. 12: 108, 2020
  9. Suda K, Cruz Diaz LA, Yoshihara K, Nakaoka H, Yachida N, Motoyama T, Inoue I, Enomoto T. Clonal lineage from normal endometrium to ovarian clear cell carcinoma through ovarian endometriosis. Cancer Science 111: 3000-3009, 2020
  10. Hata C, Nakaoka H, Xiang Y, Wang D, Yang A, Liu D, Liu F, Zou Q, Wei L, Zheng K, Inoue I, You H. Germline mutations of multiple breast cancer-related genes are differentially associated with triple-negative breast cancers and prognostic factors. J Hum Genet 65: 577-587, 2020
  11. Nakayama A, Nakatochi M, Kawamura Y, Yamamoto K, Nakaoka H, Shimizu S, Higashino T, Koyama T, Hishida A, Kuriki K, Watanabe M, Shimizu T, Ooyama K, Ooyama H, Nagase M, Hidaka Y, Matsui D, Tamura T, Nishiyama T, Shimanoe C, Katsuura-Kamano S, Takashima N, Shirai Y, Kawaguchi M, Takao M, Sugiyama R, Takada Y, Nakamura T, Nakashima H, Tsunoda M, Danjoh I, Hozawa A, Hosomichi K, Toyoda Y, Kubota Y, Takada T, Suzuki H, Stiburkova B, Major TJ, Merriman TR, Kuriyama N, Mikami H, Takezaki T, Matsuo K, Suzuki S, Hosoya T, Kamatani Y, Kubo M, Ichida K, Wakai K, Inoue I, Okada Y, Shinomiya N, Matsuo H on behalf of Japan Gout Genomics Consortium (Japan Gout). Subtype-specific gout susceptibility loci and enrichment of selection pressure on ABCG2 and ALDH2 identified by subtype genome-wide meta-analyses of clinically-defined gout patients. Ann Rheum Dis. 79: 657-665, 2020
  12. Tamura R, Yoshihara K, Nakaoka H, Yachida N, Yamaguchi M, Suda K, Ishiguro T, Nishino K, Ichikawa H, Honma K, Kikuchi A, Ueda Y, Takei Y, Fujiwara H, Motoyama T, Okuda S, Wakai T, Inoue I, Enomoto T. XCL1 expression correlates with CD8 positive T cells infiltration and PD-L1 expression in squamous cell carcinoma arising from mature cystic teratoma of the ovary. Oncogene 39: 3541-3554, 2020
  13. Higashino T, Morimoto K, Nakaoka H*, Toyoda Y, Kawamura Y, Shimizu S, Nakamura T, Hosomichi K, Nakayama A, Ooyama K, Ooyama H, Shimizu T, Ueno M, Ito T, Tamura T, Naito M, Nakashima H, Kawaguchi M, Takao M, Kawai Y, Osada N, Ichida K, Yamamoto K, Suzuki H, Shinomiya N, Inoue I, Takada T, Matsuo H. Dysfunctional missense variant of OAT10/SLC22A13 decreases gout risk and serum uric acid levels. Ann Rheum Dis. 79: 164-166, 2020

2019

  1. Miyagawa T, Hasegawa K, Aoki Y, Watanabe T, Otagiri Y, Arasaki K, Wakana Y, Asano K, Tanaka M, Yamaguchi H, Tagaya M, and Inoue H: MT1-MMP recruits the ER-Golgi SNARE Bet1 for efficient MT1-MMP transport to the plasma membrane. Journal of Cell Biology 218: 3355-3371, 2019.
  2. Miyamoto S, Narita T, Komiya M, Fujii G, Hamoya T, Nakanishi R, Tamura S, Kurokawa T, Takahashi M, and Mutoh M: Novel screening system revealed that intracellular cholesterol trafficking can be a good target for colon cancer prevention. Scientific Reports 9: 6192, 2019.

2018

  1. Sasaki K, Tsuchiya T, and Osaki T: Isolation of Endogenous Peptides from Cultured Cell Conditioned Media for Mass Spectrometry. Methods in Molecular Biology 1719: 51-58, 2018.
  2. Yamaguchi S, Fujii T, Izumi Y, Fukumura Y, Han M, Yamaguchi H, Akita T, Yamashita C, Kato S, and Sekiya T: Identification and characterization of a novel adenomatous polyposis coli mutation in adult pancreatoblastoma. Oncotarget 9: 10818-10827, 2018.
  3. Ikenoue T, Terakado Y, Zhu C, Liu X, Ohsugi T, Matsubara D, Fujii T, Kakuta S, Kubo S, Shibata T, Yamaguchi K, Iwakura Y, and Furukawa Y: Establishment and analysis of a novel mouse line carrying a conditional knockin allele of a cancer-specific FBXW7 mutation. Scientific Reports 8: 2021, 2018.
  4. Mizunoe Y, Watanabe S, Sudo Y, Kobayashi M, Yasukawa H, Natori D, Negishi A, Hoshino A, Negishi A, Okita N, Komatsu M, and Higami Y: Trehalose protects against oxidative stress through the regulation of both Keap1-Nrf2 and autophagy pathways. Redox Biology 15: 115-124, 2018.
  5. Miyazaki M, Otomo R, Matsushima-Hibiya Y, Suzuki H, Nakajima A, Abe N, Tomiyama A, Ichimura K, Matsuda K, Watanabe T, Ochiya T, Nakagama H, Sakai R, and Enari M: The p53 activator overcomes resistance to ALK inhibitors by regulating p53-target selectivity in ALK-driven neuroblastomas. Cell Death Discovery 4: 56, 2018.
  6. Miyamoto S, Nagamura Y, Nakabo A, Okabe A, Yanagihara K, Fukami K, Sakai R, and Yamaguchi H: Aberrant alternative splicing of RHOA is associated with loss of its expression and activity in diffuse-type gastric carcinoma cells. Biochem. Biophys. Res. Comm. 495: 1942-1947, 2018.
  7. Yamamoto Y, Tomiyama A, Sasaki N, Yamaguchi H, Shirakihara T, Nakashima K, Kumagai K, Takeuchi S, Toyooka T, Otani N, Wada K, Narita Y, Ichimura K, Sakai R, Namba H, and Mori K: Intracellular cholesterol level regulates sensitivity of glioblastoma cells against temozolomide-induced cell death by modulation of caspase-8 activation via death receptor 5-accumulation and activation in the plasma membrane lipid raft. Biochem. Biophys. Res. Comm. 495: 1292-1299, 2018.

2017

  1. Kobayashi M, Takeda K, Narita T, Nagai K, Okita N, Sudo Y, Miura Y, Tsumoto H, Nakagawa Y, Shimano H, and Higami Y: Mitochondrial Intermediate Peptidase is a Novel Regulator of Sirtuin-3 Activation by Caloric Restriction. FEBS letters 591: 4067-4073, 2017.
  2. Okita N, Higami Y, Fukai F, Kobayashi M, Mitarai M, Sekiya T, and Sasaki T: Modified Western blotting for insulin and other diabetes-associated peptide hormones. Scientific Reports 7: 6949, 2017.
  3. Fujii N, Narita T, Okita N, Furuta Y, Chujo Y, Sakai M, Yamada A, Takeda K, Konishi T, Sudo Y, Shimokawa I, and Higami Y: Sterol Regulatory Element-Binding Protein-1c Orchestrates Metabolic Remodeling of White Adipose Tissue by Caloric Restriction. Aging Cell 16: 508-517, 2017.
  4. Mizunoe Y, Sudo Y, Okita N, Hiraoka H, Mikami K, Narahara T, Negishi A, Yoshida M, Higashibata R, Watanabe S, Kaneko H, Natori D, Furuichi T, Kobayashi M, and Higami Y: Involvement of Lysosomal Dysfunction in Autophagosome Accumulation and Early Pathologies in Adipose Tissue of Obese Mice. Autophagy 13: 642-653, 2017.
  5. Sato H, Niimi A, Yasuhara T, Permata TBM, Hagiwara Y, Isono M, Nuryadi E, Sekine R, Oike T, Kakoti S, Yoshimoto Y, Held KD, Suzuki Y, Kono K, Miyagawa K, Nakano T, and Shibata A: DNA double-strand break repair pathway regulates PD-L1 expression in cancer cells. Nature Communications 8: 1751, 2017.
  6. Sakasai R, Isono M, Wakasugi M, Hashimoto M, Sunatani Y, Matsui T, Shibata A, Matsunaga T, and Iwabuchi K: Aquarius is required for proper CtIP expression and homologous recombination repair. Scientific Reports 7: 13808, 2017.
  7. Nakajima NI, Niimi A, Isono M, Oike T, Sato H, Nakano T, and Shibata A: Inhibition of the HDAC/Suv39/G9a pathway restores the expression of DNA damage-dependent major histocompatibility complex class I-related chain A and B in cancer cells. Oncology Reports 38: 693-702, 2017.
  8. Isono M, Niimi A, Oike T, Hagiwara Y, Sato H, Sekine R, Yoshida Y, Isobe SY, Obuse C, Nishi R, Petricci E, Nakada S, Nakano T, and Shibata A: BRCA1 Directs the Repair Pathway to Homologous Recombination by Promoting 53BP1 Dephosphorylation. Cell Reports 18: 520-532, 2017.
  9. Kobayashi D, Oike T, Shibata A, Niimi A, Kubota Y, Sakai M, Amornwhichet N, Yoshimoto Y, Hagiwara Y, Kimura Y, Hirota Y, Sato H, Isono M, Yoshida Y, Kohno T, Ohno T, and Nakano T: Mitotic catastrophe is a putative mechanism underlying the weak correlation between sensitivity to carbon ions and cisplatin. Scientific Reports 7: 40588, 2017.
  10. Yamaguchi H, Ito Y, Miura N, Nagamura Y, Nakabo A, Fukami K, Honda K, and Sakai R: Actinin-1 and actinin-4 play essential but distinct roles in invadopodia formation by carcinoma cells. Eur. J. Cell Biol. 96: 685-694, 2017.
  11. Nakashima K, Uekita T, Yano S, Kikuchi J, Nakanishi R, Sakamoto N, Fukumoto K, Nomoto A, Kawamoto K, Shibahara T, Yamaguchi H, and Sakai R: Novel small molecule inhibiting CDCP1-PKCδ pathway reduces tumor metastasis and proliferation. Cancer Sci. 108: 1049-1057, 2017.
  12. Terasaki M, Maeda H, Miyashita K, Tanaka T, Miyamoto S, and Mutoh M: A marine bio-functional lipid, fucoxanthinol, attenuates human colorectal cancer stem-like cell tumorigenicity and sphere formation. J. Clin. Biochem. Nutr. 61: 25-32, 2017.
  13. Onuma W, Asai D, Tomono S, Miyamoto S, Fujii G, Hamoya T, Nagano A, Takahashi S, Masumori S, Miyoshi N, Wakabayashi K, and Mutoh M: Anticarcinogenic Effects of Dried Citrus Peel in Colon Carcinogenesis Due to Inhibition of Oxidative Stress. Nutr. Cancer. 69: 855-861, 2017.
  14. Hamoya T, Miyamoto S, Tomono S, Fujii G, Nakanishi R, Komiya M, Tamura S, Fujimoto K, Toshima J, Wakabayashi K, and Mutoh M: Chemopreventive effects of a low-side-effect antibiotic drug, erythromycin, on mouse intestinal tumors. J. Clin. Biochem. Nutr. 60: 199-207, 2017.
  15. Miyamoto S, Komiya M, Fujii G, Hamoya T, Nakanishi R, Fujimoto K, Tamura S, Kurokawa Y, Takahashi M, Ijichi T, and Mutoh M: Preventive Effects of Heat- Killed Enterococcus faecalis Strain EC-12 on Mouse Intestinal Tumor Development. Int. J. Mol. Sci. 18: 826, 2017.
  16. Noma N, Fujii G, Miyamoto S, Komiya M, Nakanishi R, Shimura M, Tanuma SI, and Mutoh M: Impact of Acetazolamide, a Carbonic Anhydrase Inhibitor, on the Development of Intestinal Polyps in Min Mice. Int. J. Mol. Sci. 18: E851, 2017.

2016

  1. Fujii T, Tsunesumi S, Sagara H, Munakata M, Hisaki Y, Sekiya T, Furukawa Y, Sakamoto K, and Watanabe S: Smyd5 plays pivotal roles in both primitive and definitive hematopoiesis during zebrafish embryogenesis. Scientific Reports 6: 29157, 2016.
  2. Ikenoue T, Terakado Y, Nakagawa H, Hikiba Y, Fujii T, Matsubara D, Noguchi R, Zhu C, Yamamoto K, Kudo Y, Asaoka Y, Yamaguchi K, Ijichi H, Tateishi K, FukushimaN, Maeda S, Koike K, and Furukawa Y: A novel mouse model of intrahepatic cholangiocarcinoma induced by liver-specific Kras activation and Pten deletion. Scientific Reports 6: 23899, 2016.
  3. Kawai M, Komiyama H, Hosoya M, Okubo H, Fujii T, Yokoyama N, Sato C, Ueyama T,Okuzawa A, Goto M, Kojima Y, Takahashi M, Sugimoto K, Ishiyama S, Munakata S,Ogura D, Niwa SI, Tomiki Y, Ochiai T, and Sakamoto K: Impact of chromosome 17q deletion in the primary lesion of colorectal cancer on liver metastasis. Oncol Lett. 12: 4773-4778, 2016.

2015

  1. Okita N, Tsuchiya T, Fukushima M, Itakura K, Yuguchi K, Narita T, Hashizume Y, Sudo Y, Chiba T, Shimokawa I, and Higami Y: Chronological analysis of caloric restriction-induced alteration of fatty acid biosynthesis in white adipose tissue of rats. Experimental Gerontology 63: 59-66, 2015.
  2. Yashima Y, Sato S, Kawai T, Sugimoto T, Sato T, Kanda M, and Obi S: Intra-arterial 5-Fluorouracil and Interferon Therapy is Safe and Effective for Nonresectable Biliary Tract Adenocarcinoma. Hepatology international 9: 142-148, 2015.
  3. Fujii T, Saito M, Hasegawa T, Iwata T, Kuramoto H, Kubushiro K, Ohmura M, Ochiai K, Arai H, Sakamoto M, Motoyama T, and Aoki D: Performance of p16INK4a/Ki-67 immunocytochemistry for identifying CIN2+ in atypical squamous cells of undetermined significance and low-grade squamous intraepithelial lesion specimens: a Japanese Gynecologic Oncology Group study.　Int J Clin Oncol　20: 134-42, 2015.
  4. Nakano S, Morimoto S, Suzuki S, Tsushima H, Yamanaka K, Sekigawa I, and Takasaki Y: Immuno-regulatory Role of IL-35 in T Cells from Patients with Rheumatoid Arthritis. Rheumatology (Oxford) 54: 1498-1506, 2015.

2014

  1. Hatachi G, Tsuchiya T, Miyazaki T, Matsumoto K, Yamasaki N, Okita N, Nagashima A, Higami Y, and Nagayasu T: Poly(ADP-ribose) Polymerase Inhibitor (PJ34) Reduces Pulmonary Ischemia-Reperfusion Injury in Rats. Transplantation 98: 618-624, 2014.
  2. Sugimoto T, Yoichi T, Suzuki K, Kawai T, Yashima Y, Sato S, Kawamoto J, and Obi S: Endoscopic Submucosal Dissection to Treat Ileal High-grade Dysplasia after Ileoanal Anastomosis for Familial Adenomatous Polyposis: Report of a case. Clinical journal of gastroenterology 7: 481-483, 2014.
  3. Takahashi E, Koshiishi H, Sakaniwa N, Okunaka T, Takei H, Hayahsi N, Takahashi M, and Ikeda N: Photodynamic therapy for multiple central type lung cancer-A case report. Jpn J Cancer Chemother 41: 2042-2043, 2014.
  4. Kikuchi R, Kikuchi Y, Tsuda H, Maekawa H, Kozaki KI, Imoto I, Tamai S, Shiotani A Iwaya K, Sakamoto M, Sekiya T, Matsubara O., The expression and clinical significance of connective tissue growth factor in advanced head and neck squamous cell cancer. Human Cell 27: 121-128, 2014.
  5. Mikami M, Y, Sakamoto M, Shimada M, Takeshima N, Fujiwara H, Matsumoto T, Kita T, and Takizawa K: Disease Committee of Uterine Cervical and Vulvar Cancer, Japanese Gynecologic Oncology Group, Surgical Principles for Managing Stage IB2, IIA2, and IIB, Uterine Cervical Cancer (Bulky Tumors) in Japan, A Survey of the Japanese Gynecologic Oncology Group. Int J Gynecol Cancer 24: 1333-1340, 2014.